The first thing you should probably do is to protect yourself. When you expose yourself to nature you may get some harsh results without proper protection. The weather is normally hot during the gardening season so you should make sure your head is protected with a good hat. This will keep the sun from your face and help protect you from sunburn.
You will want to invest in a pair of quality gardening gloves to protect yourself from sharp briars, fertilizers and bug bites. You can find gloves made especially for your gardening needs at your local department store or online if you prefer. The clothes you wear while you are in your garden should be something you do not mind getting dirty or stained. You will be dealing with dirt; mud, spray chemicals and nature, so wear clothes that will take the heat.
If you choose to use spray pesticides a mask to wear while you are spraying your plants would be wise so you will not breath the fumes from your sprayer.